Abstract: Computation of three dimensional fluid interface instability with random perturbation is performed on a 8 CPU personal parallel computer system.The parallel computation platform is a message passage interface (MPI).A second order TVD scheme with Ghost method is applied with a fully parallel algorithm to the 3D Euler equations.Level Set function is used to track the motion of a fluid interface in an Eulerian framework.Buffer zone and data communication are discussed.The number of computation meshes is about 1 million.Bubble evolution with random perturbation in Rayleigh Taylor instability is obtained by numerical simulation.