Abstract: In this paper, the NOR neuron logic gate is constructed by using the Morris-lecar (ML) neuron model, and the NOR neuron logic gate is implanted into the two-dimensional neural network. When plane waves pass through the logic gate region in the network, it is observed that the NOR neuron logic gate induced the spontaneous generation of spiral waves. Appropriately increasing the coupling strength between neurons in logic gate to make the logic gates have no output, which can either prevent the logic gate to induce spiral wave, but also make spiral wave induced by the logic gate disappear. The physical mechanism underlying these phenomena is theoretically analyzed.These research results are helpful for people to grasp the spontaneous generation mechanism of spiral waves in the brain, which is conducive to propose effective method to treat epileptic diseases.